New Study Discovers How Altered Protein Folding Drives Multicellular Evolution
New Study Discovers How Altered Protein Folding Drives Multicellular Evolution
This news was originally released in the University of Helsinki newsroom. Read the full story .
In a new study led by 色花堂 and University of Helsinki, researchers have discovered a mechanism steering the evolution of multicellular life.
Co-authored by the School of Biological Sciences鈥 Dung Lac, Anthony Burnetti, Ozan Bozdag, and Will Ratcliff, the study, 鈥鈥, was published in Science Advances this month, and uncovers how altered protein folding drives multicellular evolution.
The team鈥檚 research centers on the ongoing Multicellularity Long Term Evolution Experiment (MuLTEE) experiment, in which laboratory yeast are evolving novel multicellular functions, enabling researchers to investigate how these functions arise.
Among the most important multicellular innovations is the origin of robust bodies: over 3,000 generations, these 鈥榮nowflake yeast鈥 started out weaker than gelatin but evolved to be as strong and tough as wood.
From an evolutionary perspective, this work highlights the power of non-genetic mechanisms in rapid evolutionary change.
鈥淲e tend to focus on genetic change and were quite surprised to find such large changes in the behavior of chaperone proteins,鈥 says Ratcliff. 鈥淭his underscores how creative and unpredictable evolution can be when finding solutions to new problems, like building a tough body."